Easily one of the common failures in website design, failing to account for the use of different kinds of browsers is a big no-no that results in many users leaving your website. Though Chrome may be the most popular browser, many millions use other browsers, and you dont want them to get a bad impression of your website.
? Off-putting Fonts
Keep it simple and beautiful, so long as it remains readable. Selecting crazy fonts with grand flourishes will just make the site and its contents unreadable - rendering it useless. The idea is to convey information first, and be beautiful after.